BDBM620119 (R)-1-(5-(3-methylmorpholino)-3-(1H-pyrazol-5-yl)isothiazolo[4,5-b] pyridin-7-yl)cyclopropane-1-carbonitrile::US20230295166, Compound 51::US20230295166, Compound 53

SMILES C[C@@H]1COCCN1c1cc(c2snc(-c3ccn[nH]3)c2n1)C1(CC1)C#N

InChI Key InChIKey=VUPQEZMOMWHFQY-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 620119   

TargetSerine/threonine-protein kinase ATR(Human)
Antengene Discovery

US Patent
LigandPNGBDBM620119((R)-1-(5-(3-methylmorpholino)-3-(1H-pyrazol-5-yl)i...)
Affinity DataIC50: 100nMAssay Description:Detection of ATR kinase activity utilized the Mobility shift assay to measure the phosphorylation of the substrate protein FAM-RAD17 (GL, Cat. No. 51...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2023
Entry Details
Go to US Patent

TargetSerine/threonine-protein kinase ATR(Human)
Antengene Discovery

US Patent
LigandPNGBDBM620119((R)-1-(5-(3-methylmorpholino)-3-(1H-pyrazol-5-yl)i...)
Affinity DataIC50: 100nMAssay Description:Detection of ATR kinase activity utilized the Mobility shift assay to measure the phosphorylation of the substrate protein FAM-RAD17 (GL, Cat. No. 51...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2023
Entry Details
Go to US Patent