BDBM620116 (3R)-4-[4-(diethylphosphoryl)-7-(1H-pyrazol-5-yl)imidazo [1,5-b]pyridazin-2-yl]-3-methylmorpholine::US20230295166, Compound 39

SMILES CCP(=O)(CC)c1cc(nn2c(ncc12)-c1ccn[nH]1)N1CCOC[C@H]1C

InChI Key InChIKey=QOTKIJOKFMTPFM-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 620116   

TargetSerine/threonine-protein kinase ATR(Human)
Antengene Discovery

US Patent
LigandPNGBDBM620116((3R)-4-[4-(diethylphosphoryl)-7-(1H-pyrazol-5-yl)i...)
Affinity DataIC50: 100nMAssay Description:Detection of ATR kinase activity utilized the Mobility shift assay to measure the phosphorylation of the substrate protein FAM-RAD17 (GL, Cat. No. 51...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2023
Entry Details
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