BDBM620115 (R)-3-methyl-4-(4-(1-methyl-1H-pyrazol-5-yl)-7-(3-methyl-1H-pyrazol-5-yl)imidazo[1,5-b]pyridazin-2-yl)morpholine::US20230295166, Compound 34

SMILES C[C@@H]1COCCN1c1cc(-c2ccnn2C)c2cnc(-c3cc(C)n[nH]3)n2n1

InChI Key InChIKey=QYXXEWUIQNXNAJ-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 620115   

TargetSerine/threonine-protein kinase ATR(Human)
Antengene Discovery

US Patent

LigandBDBM620115((R)-3-methyl-4-(4-(1-methyl-1H-pyrazol-5-yl)-7-(3-...)Copy SMILESCopy InChI

Affinity DataIC50: 100nMAssay Description:Detection of ATR kinase activity utilized the Mobility shift assay to measure the phosphorylation of the substrate protein FAM-RAD17 (GL, Cat. No. 51...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
10/30/2023
Entry Details
Copy Entry DOIGo to US Patent

Copy Rxn URL