BDBM620098 (R)-4-(7-(2-fluoropyridin-3-yl)-3-(1H-pyrazol-5-yl)pyrazolo[1,5-alpyrimidin-5-yl)-3-methylmorpholine::US20230295166, Compound 6

SMILES C[C@@H]1COCCN1c1cc(-c2cccnc2F)n2ncc(-c3ccn[nH]3)c2n1

InChI Key InChIKey=BZXOEHNCMHMYAW-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 620098   

TargetSerine/threonine-protein kinase ATR(Human)
Antengene Discovery

US Patent
LigandPNGBDBM620098((R)-4-(7-(2-fluoropyridin-3-yl)-3-(1H-pyrazol-5-yl...)
Affinity DataIC50: 100nMAssay Description:Detection of ATR kinase activity utilized the Mobility shift assay to measure the phosphorylation of the substrate protein FAM-RAD17 (GL, Cat. No. 51...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2023
Entry Details
Go to US Patent