BDBM6196 Methoxy Aniline 5::N-(2-Chloro-5-methoxyphenyl)-6-methoxy-7-(3-morpholin-4-ylpropoxy)quinazolin-4-amine::N-(2-chloro-5-methoxyphenyl)-6-methoxy-7-[3-(morpholin-4-yl)propoxy]quinazolin-4-amine

SMILES COc1ccc(Cl)c(Nc2ncnc3cc(OCCCN4CCOCC4)c(OC)cc23)c1

InChI Key InChIKey=CVOJFSBJHSHLQV-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 6196   

LigandPNGBDBM6196(N-(2-Chloro-5-methoxyphenyl)-6-methoxy-7-(3-morpho...)
Affinity DataIC50: 1.18E+3nMT: 2°CAssay Description:An ELISA assay was used to determine the ability of inhibitor to inhibit VEGF-RRTK activity. The compounds were incubated with enzyme 20 min at room ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/18/2005
Entry Details Article
PubMed
LigandPNGBDBM6196(N-(2-Chloro-5-methoxyphenyl)-6-methoxy-7-(3-morpho...)
Affinity DataIC50: 10nMpH: 7.4 T: 2°CAssay Description:This assay determines the ability of test compounds to inhibit Src kinase activity that catalyzes the transfer of the terminal phosphate to the immob...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/18/2005
Entry Details Article
PubMed