BDBM619407 US20230295130, Example T-31

SMILES COC(=O)Nc1ccc2c(c[nH]c2c1Br)-c1nc(NC2CC3(CC(N)C3)C2)ncc1C(F)(F)F

InChI Key InChIKey=JICAIOWSCOLKSA-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 619407   

LigandPNGBDBM619407(US20230295130, Example T-31)
Affinity DataIC50: 50nMAssay Description:1) The compound solution and the positive control were diluted 8.3 times with double distilled water and then added to the 384 well plate, each conce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2023
Entry Details
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TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Human)
Tyk Medicines

US Patent
LigandPNGBDBM619407(US20230295130, Example T-31)
Affinity DataIC50: 500nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2023
Entry Details
Go to US Patent

TargetCyclin-T1/Cyclin-dependent kinase 9(Human)
Tyk Medicines

US Patent
LigandPNGBDBM619407(US20230295130, Example T-31)
Affinity DataIC50: 500nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2023
Entry Details
Go to US Patent

TargetCyclin-K/Cyclin-dependent kinase 12(Human)
Tyk Medicines

US Patent
LigandPNGBDBM619407(US20230295130, Example T-31)
Affinity DataIC50: 500nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2023
Entry Details
Go to US Patent