BDBM619383 US20230295130, Example T-07

SMILES CC1(C)COC(Nc2ccc3c(c[nH]c3c2Br)-c2nc(N[C@H]3CCCNC3)ncc2C(F)(F)F)=N1

InChI Key InChIKey=UIUZXJMVBGOWMB-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 619383   

LigandPNGBDBM619383(US20230295130, Example T-07)
Affinity DataIC50: 50nMAssay Description:1) The compound solution and the positive control were diluted 8.3 times with double distilled water and then added to the 384 well plate, each conce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2023
Entry Details
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TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Human)
Tyk Medicines

US Patent
LigandPNGBDBM619383(US20230295130, Example T-07)
Affinity DataIC50: 500nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2023
Entry Details
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TargetCyclin-T1/Cyclin-dependent kinase 9(Human)
Tyk Medicines

US Patent
LigandPNGBDBM619383(US20230295130, Example T-07)
Affinity DataIC50: 500nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2023
Entry Details
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TargetCyclin-K/Cyclin-dependent kinase 12(Human)
Tyk Medicines

US Patent
LigandPNGBDBM619383(US20230295130, Example T-07)
Affinity DataIC50: 500nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2023
Entry Details
Go to US Patent