BDBM619381 US20230295130, Example T-05

SMILES CN1CCC[C@@H](C1)Nc1ncc(c(n1)-c1c[nH]c2cc(ccc12)N1CCCC1=O)C(F)(F)F

InChI Key InChIKey=QTNJODOYENNLKJ-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 619381   

LigandPNGBDBM619381(US20230295130, Example T-05)
Affinity DataIC50: 50nMAssay Description:1) The compound solution and the positive control were diluted 8.3 times with double distilled water and then added to the 384 well plate, each conce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2023
Entry Details
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TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Human)
Tyk Medicines

US Patent
LigandPNGBDBM619381(US20230295130, Example T-05)
Affinity DataIC50: 500nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2023
Entry Details
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TargetCyclin-T1/Cyclin-dependent kinase 9(Human)
Tyk Medicines

US Patent
LigandPNGBDBM619381(US20230295130, Example T-05)
Affinity DataIC50: 500nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2023
Entry Details
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TargetCyclin-K/Cyclin-dependent kinase 12(Human)
Tyk Medicines

US Patent
LigandPNGBDBM619381(US20230295130, Example T-05)
Affinity DataIC50: 500nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2023
Entry Details
Go to US Patent