BDBM619075 US20230295119, Compound 9U

SMILES CCN(C)Cc1ccc(Nc2cc(Nc3cccc(-c4ncn(C)n4)c3OC)c(cn2)C(=O)CC)nc1

InChI Key InChIKey=UDLZTKXUBVKICY-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 619075   

TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Gossamer Bio Services

US Patent
LigandPNGBDBM619075(US20230295119, Compound 9U)
Affinity DataIC50: 5nMAssay Description:Compounds described herein were tested for the ability to inhibit activity of human JAK1, JAK2 and JAK3, which was achieved using TR-FRET assays. Bri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2023
Entry Details
Go to US Patent

TargetTyrosine-protein kinase JAK1(Human)
Gossamer Bio Services

US Patent
LigandPNGBDBM619075(US20230295119, Compound 9U)
Affinity DataIC50: 500nMAssay Description:Compounds described herein were tested for the ability to inhibit activity of human JAK1, JAK2 and JAK3, which was achieved using TR-FRET assays. Bri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2023
Entry Details
Go to US Patent

TargetTyrosine-protein kinase JAK2(Human)
Gossamer Bio Services

US Patent
LigandPNGBDBM619075(US20230295119, Compound 9U)
Affinity DataIC50: 500nMAssay Description:Compounds described herein were tested for the ability to inhibit activity of human JAK1, JAK2 and JAK3, which was achieved using TR-FRET assays. Bri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2023
Entry Details
Go to US Patent

TargetTyrosine-protein kinase JAK3(Human)
Gossamer Bio Services

US Patent
LigandPNGBDBM619075(US20230295119, Compound 9U)
Affinity DataIC50: 500nMAssay Description:Compounds described herein were tested for the ability to inhibit activity of human JAK1, JAK2 and JAK3, which was achieved using TR-FRET assays. Bri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2023
Entry Details
Go to US Patent