BDBM618078 US20230286970, Compound 23

SMILES Cn1c(N)nc2cc(ccc12)-c1cn(Cc2ccc(cc2)-c2nnc(o2)C(F)F)nn1

InChI Key InChIKey=ZTDYHKPOGGEUGI-UHFFFAOYSA-N

Data  11 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 618078   

TargetHistone deacetylase 6(Human)
Italfarmaco

US Patent
LigandPNGBDBM618078(US20230286970, Compound 23)
Affinity DataIC50: 13nMAssay Description:For each test compound, 100× concentrated DMSO solutions at 8 doses were prepared and then diluted in assay buffer (25 mM Tris-HCl, pH 8, 130 mM NaCl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2023
Entry Details
US Patent

TargetHistone deacetylase 8(Human)
Italfarmaco

US Patent
LigandPNGBDBM618078(US20230286970, Compound 23)
Affinity DataIC50: 565nMAssay Description:For each test compound, 100× concentrated DMSO solutions at 8 doses were prepared and then diluted in assay buffer (25 mM Tris-HCl, pH 8, 130 mM NaCl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2023
Entry Details
US Patent

TargetHistone deacetylase 3(Human)
Italfarmaco

US Patent
LigandPNGBDBM618078(US20230286970, Compound 23)
Affinity DataIC50: 2.65E+4nMAssay Description:For each test compound, 100× concentrated DMSO solutions at 8 doses were prepared and then diluted in assay buffer (25 mM Tris-HCl, pH 8, 130 mM NaCl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2023
Entry Details
US Patent

TargetPolyamine deacetylase HDAC10(Human)
Italfarmaco

US Patent
LigandPNGBDBM618078(US20230286970, Compound 23)
Affinity DataIC50: 3.00E+4nMAssay Description:For each test compound, 100× concentrated DMSO solutions at 8 doses were prepared and then diluted in assay buffer (25 mM Tris-HCl, pH 8, 130 mM NaCl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2023
Entry Details
US Patent

TargetHistone deacetylase 11(Human)
Italfarmaco

US Patent
LigandPNGBDBM618078(US20230286970, Compound 23)
Affinity DataIC50: 3.00E+4nMAssay Description:For each test compound, 100× concentrated DMSO solutions at 8 doses were prepared and then diluted in assay buffer (25 mM Tris-HCl, pH 8, 130 mM NaCl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2023
Entry Details
US Patent

TargetHistone deacetylase 5(Human)
Italfarmaco

US Patent
LigandPNGBDBM618078(US20230286970, Compound 23)
Affinity DataIC50: 3.00E+4nMAssay Description:For each test compound, 100× concentrated DMSO solutions at 8 doses were prepared and then diluted in assay buffer (25 mM Tris-HCl, pH 8, 130 mM NaCl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2023
Entry Details
US Patent

TargetHistone deacetylase 7(Human)
Italfarmaco

US Patent
LigandPNGBDBM618078(US20230286970, Compound 23)
Affinity DataIC50: 3.00E+4nMAssay Description:For each test compound, 100× concentrated DMSO solutions at 8 doses were prepared and then diluted in assay buffer (25 mM Tris-HCl, pH 8, 130 mM NaCl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2023
Entry Details
US Patent

TargetHistone deacetylase 9(Human)
Italfarmaco

US Patent
LigandPNGBDBM618078(US20230286970, Compound 23)
Affinity DataIC50: 3.00E+4nMAssay Description:For each test compound, 100× concentrated DMSO solutions at 8 doses were prepared and then diluted in assay buffer (25 mM Tris-HCl, pH 8, 130 mM NaCl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2023
Entry Details
US Patent

TargetHistone deacetylase 2(Human)
Italfarmaco

US Patent
LigandPNGBDBM618078(US20230286970, Compound 23)
Affinity DataIC50: 3.00E+4nMAssay Description:For each test compound, 100× concentrated DMSO solutions at 8 doses were prepared and then diluted in assay buffer (25 mM Tris-HCl, pH 8, 130 mM NaCl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2023
Entry Details
US Patent

TargetHistone deacetylase 4(Human)
Italfarmaco

US Patent
LigandPNGBDBM618078(US20230286970, Compound 23)
Affinity DataIC50: 3.00E+4nMAssay Description:For each test compound, 100× concentrated DMSO solutions at 8 doses were prepared and then diluted in assay buffer (25 mM Tris-HCl, pH 8, 130 mM NaCl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2023
Entry Details
US Patent

TargetHistone deacetylase 1(Human)
Italfarmaco

US Patent
LigandPNGBDBM618078(US20230286970, Compound 23)
Affinity DataIC50: 3.03E+4nMAssay Description:For each test compound, 100× concentrated DMSO solutions at 8 doses were prepared and then diluted in assay buffer (25 mM Tris-HCl, pH 8, 130 mM NaCl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2023
Entry Details
US Patent