BDBM617577 US20230286943, Example 45

SMILES CCn1nccc1C(=O)N[C@@H]([C@H]1CC[C@H](C)CC1)C(=O)Nc1ccc(cn1)-c1c(C)cnn1C

InChI Key InChIKey=CLQAAYZHCVVKBK-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 617577   

TargetInterleukin-17F(Human)
Sanofi

US Patent
LigandPNGBDBM617577(US20230286943, Example 45)
Affinity DataIC50: 50.1nMAssay Description:The ability of the compounds to block binding of IL-17A to its receptor, IL-17RA, was analysed in a competition assay using AlphaLISA technology (Per...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2023
Entry Details
Go to US Patent