BDBM617517 US20240041837, Example 11::US20240041837, Example 6

SMILES CCOc1ccc(cc1CC(O)=O)-c1cccc(CCCc2nn(Cc3ccc(cc3)C(C)(C)C)c(=O)n2CC)c1

InChI Key InChIKey=KUPVZYDOHAPPNF-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 617517   

TargetPeroxisome proliferator-activated receptor alpha(Human)
Tempest Therapeutics

US Patent
LigandPNGBDBM617517(US20240041837, Example 6 | US20240041837, Example ...)
Affinity DataIC50: 58nMAssay Description:To determine species selectivity, a Mouse PPARα Reporter Assay System was used (Indigo Biosciences, Cat. #M00111). Activity of test compounds to...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2024
Entry Details
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TargetPeroxisome proliferator-activated receptor delta(Human)
Tempest Therapeutics

US Patent
LigandPNGBDBM617517(US20240041837, Example 6 | US20240041837, Example ...)
Affinity DataIC50: 1.33E+4nMAssay Description:To determine species selectivity, a Mouse PPARα Reporter Assay System was used (Indigo Biosciences, Cat. #M00111). Activity of test compounds to...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2024
Entry Details
Go to US Patent

TargetPeroxisome proliferator-activated receptor gamma(Human)
Tempest Therapeutics

US Patent
LigandPNGBDBM617517(US20240041837, Example 6 | US20240041837, Example ...)
Affinity DataIC50: 3.98E+4nMAssay Description:To determine species selectivity, a Mouse PPARα Reporter Assay System was used (Indigo Biosciences, Cat. #M00111). Activity of test compounds to...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2024
Entry Details
Go to US Patent

TargetThyroid hormone receptor beta(Human)
Tempest Therapeutics

US Patent
LigandPNGBDBM617517(US20240041837, Example 6 | US20240041837, Example ...)
Affinity DataIC50: 3.08E+4nMAssay Description:To determine species selectivity, a Mouse PPARα Reporter Assay System was used (Indigo Biosciences, Cat. #M00111). Activity of test compounds to...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2024
Entry Details
Go to US Patent

TargetGlucocorticoid receptor(Human)
Tempest Therapeutics

US Patent
LigandPNGBDBM617517(US20240041837, Example 6 | US20240041837, Example ...)
Affinity DataIC50: 1.82E+4nMAssay Description:To determine species selectivity, a Mouse PPARα Reporter Assay System was used (Indigo Biosciences, Cat. #M00111). Activity of test compounds to...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2024
Entry Details
Go to US Patent

TargetEstrogen receptor beta(Human)
Tempest Therapeutics

US Patent
LigandPNGBDBM617517(US20240041837, Example 6 | US20240041837, Example ...)
Affinity DataIC50: 1.94E+4nMAssay Description:To determine species selectivity, a Mouse PPARα Reporter Assay System was used (Indigo Biosciences, Cat. #M00111). Activity of test compounds to...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2024
Entry Details
Go to US Patent

TargetPeroxisome proliferator-activated receptor alpha(Human)
Tempest Therapeutics

US Patent
LigandPNGBDBM617517(US20240041837, Example 6 | US20240041837, Example ...)
Affinity DataIC50: 58nMAssay Description:The screening of test compounds for agonist or antagonist activities against human PPARα receptors was performed using a commercial kit, Human P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2024
Entry Details
Go to US Patent

TargetPeroxisome proliferator-activated receptor alpha(Human)
Tempest Therapeutics

US Patent
LigandPNGBDBM617517(US20240041837, Example 6 | US20240041837, Example ...)
Affinity DataIC50: 48nMAssay Description:The screening of test compounds for agonist or antagonist activities against human PPARα receptors was performed using a commercial kit, Human P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2024
Entry Details
Go to US Patent