BDBM617472 US20230285393, Compound 020

SMILES FC1(F)CC(C1)C(=O)N1Cc2ccc(cc2C1)-c1nccc(Nc2ccc(cc2)-c2cn[nH]c2)n1

InChI Key InChIKey=PPNGOBGQHGDLAT-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 617472   

TargetRho-associated protein kinase 2 [1-119](Human)
Beijing Tide Pharmaceutical

US Patent
LigandPNGBDBM617472(US20230285393, Compound 020)
Affinity DataIC50: 44nMAssay Description:The kinase IC50 was determined by a commercialized CISBIO kinase detection kit, HTRF KinEASE-STK S2 kit (62ST2PEC). ROCK2 (01-119) employed in the re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2023
Entry Details
Go to US Patent