BDBM617439 US20230285377, Example 25

SMILES CC(C)c1cc(C(=O)N[C@@H](C)c2cc(no2)-c2ccnc(c2)C(F)(F)F)n(C)n1

InChI Key InChIKey=DCSRITCIUWGXPY-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 617439   

TargetPotassium channel subfamily T member 1(Human)
Praxis Precision Medicines

US Patent
LigandPNGBDBM617439(US20230285377, Example 25)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of KCNT1 (KNa1.1, Slack) was evaluated using a tetracycline inducible cell line (HEK-TREX). Currents were recorded using the SyncroPatch 3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2023
Entry Details
Go to US Patent