BDBM617413 US20230285377, Example 2

SMILES C[C@H](NC(=O)c1cc(nn1C)C(F)(F)F)c1cc(no1)-c1ccnc(c1)C(F)(F)F

InChI Key InChIKey=JIOVXRZLAZOVCS-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 617413   

TargetPotassium channel subfamily T member 1(Human)
Praxis Precision Medicines

US Patent
LigandPNGBDBM617413(US20230285377, Example 2)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of KCNT1 (KNa1.1, Slack) was evaluated using a tetracycline inducible cell line (HEK-TREX). Currents were recorded using the SyncroPatch 3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2023
Entry Details
Go to US Patent