BDBM617078 US11753373, Compound D-3-c::US12186309, Compound 20

SMILES CC(C)(C)[C@H](NC(=O)C(F)F)C(=O)N1C[C@H]2[C@@H]([C@H]1C(=O)N[C@@H](C[C@@H]1CCCNC1=O)C#N)C2(C)C

InChI Key InChIKey=SAGCWYXFUIQBSK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 617078   

TargetReplicase polyprotein 1ab(2019-nCoV)
Acea Therapeutics

US Patent
LigandPNGBDBM617078(US11753373, Compound D-3-c | US12186309, Compound ...)
Affinity DataIC50: 4.79nMAssay Description:Mpro activity was measured according to the manufacturer's protocol (BPS Biosciences, cat #78042-2) in 384-well plates. The included recombinant un-t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2023
Entry Details
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TargetReplicase polyprotein 1a(2019-nCoV)
University of Alberta

US Patent
LigandPNGBDBM617078(US11753373, Compound D-3-c | US12186309, Compound ...)
Affinity DataIC50: 100nMAssay Description:A synthesized fluorescent substrate containing the cleavage site (indicated by the arrow, ↓) of SARS-CoV-2 3CLP (2-Abz-SVTLQ↓SG-Tyr(NO2)—R—NH2) was u...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2025
Entry Details
Go to US Patent