BDBM616854 6-(3-chlorobenzyl)-5-methyl-2-((1-phenylpiperidin-4-yl)methyl)-[1,2,4]triazolo[1,5-a]pyrimidin-7(4H)-one ::US20230279008, Compound 47

SMILES Cc1[nH]c2nc(CC3CCN(CC3)c3ccccc3)nn2c(=O)c1Cc1cccc(Cl)c1

InChI Key InChIKey=JJEVBHCFWHAPJY-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 616854   

TargetProstaglandin reductase 2(Human)
National Health Research Institutes

US Patent
LigandPNGBDBM616854(US20230279008, Compound 47 | 6-(3-chlorobenzyl)-5-...)
Affinity DataIC50: 2.60nMAssay Description:Exemplary compounds thus prepared were evaluated for their efficacy in inhibiting PTGR2. In vitro enzyme activity was measured to determine the half ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2023
Entry Details
US Patent

TargetProstaglandin reductase 2(Human)
National Health Research Institutes

US Patent
LigandPNGBDBM616854(US20230279008, Compound 47 | 6-(3-chlorobenzyl)-5-...)
Affinity DataEC50:  546nMAssay Description:Exemplary compounds thus prepared were evaluated for their efficacy in inhibiting PTGR2. In vitro enzyme activity was measured to determine the half ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2023
Entry Details
US Patent