BDBM616843 6-(3-fluoro-4-methoxybenzyl)-5-methyl-2-(1-(4-phenylpiperazin-1-yl)ethyl)-[1,2,4]triazolo[1,5-a]pyrimidin-7(4H)-one ::US20230279008, Compound 15

SMILES COc1ccc(Cc2c(C)[nH]c3nc(nn3c2=O)C(C)N2CCN(CC2)c2ccccc2)cc1F

InChI Key InChIKey=GTXOMMNPQAUOIO-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 616843   

TargetProstaglandin reductase 2(Human)
National Health Research Institutes

US Patent
LigandPNGBDBM616843(US20230279008, Compound 15 | 6-(3-fluoro-4-methoxy...)
Affinity DataIC50: 33.9nMAssay Description:Exemplary compounds thus prepared were evaluated for their efficacy in inhibiting PTGR2. In vitro enzyme activity was measured to determine the half ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2023
Entry Details
US Patent

TargetProstaglandin reductase 2(Human)
National Health Research Institutes

US Patent
LigandPNGBDBM616843(US20230279008, Compound 15 | 6-(3-fluoro-4-methoxy...)
Affinity DataEC50:  64.5nMAssay Description:Exemplary compounds thus prepared were evaluated for their efficacy in inhibiting PTGR2. In vitro enzyme activity was measured to determine the half ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2023
Entry Details
US Patent