BDBM616833 6-(4-chlorobenzyl)-2-((4-(2-methoxyphenyl)piperazin-1-yl)methyl)-5-methyl-[1,2,4]triazolo[1,5-a]pyrimidin-7(4H)-one ::US20230279008, Compound 1

SMILES COc1ccccc1N1CCN(Cc2nc3[nH]c(C)c(Cc4ccc(Cl)cc4)c(=O)n3n2)CC1

InChI Key InChIKey=FBJAJAWESWNBBP-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 616833   

TargetProstaglandin reductase 2(Human)
National Health Research Institutes

US Patent
LigandPNGBDBM616833(US20230279008, Compound 1 | 6-(4-chlorobenzyl)-2-(...)
Affinity DataIC50: 0.200nMAssay Description:Exemplary compounds thus prepared were evaluated for their efficacy in inhibiting PTGR2. In vitro enzyme activity was measured to determine the half ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2023
Entry Details
US Patent

TargetProstaglandin reductase 2(Human)
National Health Research Institutes

US Patent
LigandPNGBDBM616833(US20230279008, Compound 1 | 6-(4-chlorobenzyl)-2-(...)
Affinity DataEC50:  874nMAssay Description:Exemplary compounds thus prepared were evaluated for their efficacy in inhibiting PTGR2. In vitro enzyme activity was measured to determine the half ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2023
Entry Details
US Patent