BDBM616830 (3R,4R)-1-[1-[6-ethyl-5-(8-methylimidazo[1,2-a]pyridin-6-yl)-2-pyridyl]-4-piperidyl]-4-methoxy-pyrrolidin-3-amine::US20230279001, Example 15

SMILES CCc1nc(ccc1-c1cc(C)c2nccn2c1)N1CCC(CC1)N1C[C@@H](N)[C@@H](C1)OC

InChI Key InChIKey=WJMJKMOALKRDBX-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 616830   

TargetPotassium voltage-gated channel subfamily H member 2(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM616830(US20230279001, Example 15 | (3R,4R)-1-[1-[6-ethyl-...)
Affinity DataIC50: 2.00E+4nMAssay Description:The hERG channel inhibition assay is a highly sensitive measurement that identifies compounds exhibiting hERG inhibition related to cardiotoxicity in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2023
Entry Details
Go to US Patent