BDBM6167 1,6-naphthyridine 36::1-[3-(2,6-dichlorophenyl)-7-{[4-(diethylamino)butyl]amino}-1,6-naphthyridin-2-yl]-3-ethylurea::N-[3-(2,6-Dichlorophenyl)-7-[[4-(diethylamino)butyl]amino]-1,6-naphthyridin-2-yl]-N -ethylurea

SMILES CCNC(=O)Nc1nc2cc(NCCCCN(CC)CC)ncc2cc1-c1c(Cl)cccc1Cl

InChI Key InChIKey=QVJHVQPCRIXTMX-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 6167   

TargetPlatelet-derived growth factor receptor beta(Mouse)
University of Auckland

LigandPNGBDBM6167(1-[3-(2,6-dichlorophenyl)-7-{[4-(diethylamino)buty...)
Affinity DataIC50: 160nMAssay Description:Compounds were evaluated for their ability to prevent phosphorylation of a model glutamate-tyrosine copolymer substrate by isolated human FGFR-1, mou...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2005
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 1(Human)
University of Auckland

LigandPNGBDBM6167(1-[3-(2,6-dichlorophenyl)-7-{[4-(diethylamino)buty...)
Affinity DataIC50: 29nMAssay Description:Compounds were evaluated for their ability to prevent phosphorylation of a model glutamate-tyrosine copolymer substrate by isolated human FGFR-1, mou...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2005
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
University of Auckland

LigandPNGBDBM6167(1-[3-(2,6-dichlorophenyl)-7-{[4-(diethylamino)buty...)
Affinity DataIC50: 14nMAssay Description:Compounds were evaluated for their ability to prevent phosphorylation of a model glutamate-tyrosine copolymer substrate by isolated human FGFR-1, mou...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2005
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
University of Auckland

LigandPNGBDBM6167(1-[3-(2,6-dichlorophenyl)-7-{[4-(diethylamino)buty...)
Affinity DataIC50: 130nMAssay Description:Tha assay was using human VEGFR-2 in DELFIA (dissociation-enhanced lanthanide fluoroimmunoassay) format. IC50 is the concentration of inhibitor that ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2005
Entry Details Article
PubMed