BDBM616166 US20230271968, Compound A9

SMILES C[C@@H]1COCCN1c1cc(-c2c(C)nn(c2C)-c2cncc(F)c2)n2ncc(-c3ccn[nH]3)c2n1

InChI Key InChIKey=SQYGYXGOJYZQEI-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 616166   

TargetSerine/threonine-protein kinase ATR(Human)
Beijing Tide Pharmaceutical

US Patent
LigandPNGBDBM616166(US20230271968, Compound A9)
Affinity DataIC50: 2nMAssay Description:Biotinylated protein derived from p53 (Eurofins, art. No.: 14-952) was phosphorylated with ATR kinase. The amount of phosphorylated protein was deter...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2023
Entry Details
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TargetSerine-protein kinase ATM(Human)
Beijing Tide Pharmaceutical

US Patent
LigandPNGBDBM616166(US20230271968, Compound A9)
Affinity DataIC50: 6.37E+3nMAssay Description:Biotinylated protein derived from p53 (Eurofins, art. No.: 14-952) was phosphorylated with ATR kinase. The amount of phosphorylated protein was deter...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2023
Entry Details
Go to US Patent

TargetDNA-dependent protein kinase catalytic subunit(Human)
Beijing Tide Pharmaceutical

US Patent
LigandPNGBDBM616166(US20230271968, Compound A9)
Affinity DataIC50: 303nMAssay Description:Biotinylated protein derived from p53 (Eurofins, art. No.: 14-952) was phosphorylated with ATR kinase. The amount of phosphorylated protein was deter...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2023
Entry Details
Go to US Patent

TargetPhosphatidylinositol 3-kinase regulatory subunit alpha(Human)
Beijing Tide Pharmaceutical

US Patent
LigandPNGBDBM616166(US20230271968, Compound A9)
Affinity DataIC50: 4.06E+3nMAssay Description:Biotinylated protein derived from p53 (Eurofins, art. No.: 14-952) was phosphorylated with ATR kinase. The amount of phosphorylated protein was deter...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2023
Entry Details
Go to US Patent

LigandPNGBDBM616166(US20230271968, Compound A9)
Affinity DataIC50: 1.13E+3nMAssay Description:Biotinylated protein derived from p53 (Eurofins, art. No.: 14-952) was phosphorylated with ATR kinase. The amount of phosphorylated protein was deter...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2023
Entry Details
Go to US Patent

TargetSerine/threonine-protein kinase mTOR(Human)
Beijing Tide Pharmaceutical

US Patent
LigandPNGBDBM616166(US20230271968, Compound A9)
Affinity DataIC50: 1.83E+3nMAssay Description:Biotinylated protein derived from p53 (Eurofins, art. No.: 14-952) was phosphorylated with ATR kinase. The amount of phosphorylated protein was deter...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2023
Entry Details
Go to US Patent