BDBM614795 2-[1-(1- Cyclopropylethyl)- 1H-pyrazol-4-yl]- 5-[({1-[2-fluoro- 4- (trifluoromethyl) phenyl] cyclopropyl} carbonyl)amino] benzoic acid as::US20230271931, Example 153

SMILES CC(C1CC1)n1cc(cn1)-c1ccc(NC(=O)C2(CC2)c2ccc(cc2F)C(F)(F)F)cc1C(O)=O

InChI Key InChIKey=FAWYZGHAODSGMT-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 614795   

TargetB1 bradykinin receptor(Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM614795(US20230271931, Example 153 | 2-[1-(1- Cyclopropyle...)
Affinity DataIC50: 8.70nMAssay Description:Notably, Compound Examples are tested in the FLIPR assays in the absence (hB1 free IC50) of 0.1% BSA in assay buffer, in order to assess the potency ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2023
Entry Details
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