BDBM614791 2-(2-Cyclobutyl- 1,3-thiazol-5-yl)- 5-[({1-[2-fluoro- 4- (trifluoromethoxy) phenyl]cyclopro- pyl}carbonyl) amino]benzoic acid::US20230271931, Example 149

SMILES OC(=O)c1cc(NC(=O)C2(CC2)c2ccc(OC(F)(F)F)cc2F)ccc1-c1cnc(s1)C1CCC1

InChI Key InChIKey=XYZXYEVRQBAKGA-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 614791   

TargetB1 bradykinin receptor(Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM614791(US20230271931, Example 149 | 2-(2-Cyclobutyl- 1,3-...)
Affinity DataIC50: 3.20nMAssay Description:Notably, Compound Examples are tested in the FLIPR assays in the absence (hB1 free IC50) of 0.1% BSA in assay buffer, in order to assess the potency ...More data for this Ligand-Target Pair
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Date in BDB:
10/15/2023
Entry Details
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