BDBM614789 2-(2-Cyclobutyl- 1,3-thiazol-5-yl)- 5-({[1-(2-fluoro- 4- methylphenyl) cyclopropyl] carbonyl} amino)benzoic acid::US20230271931, Example 147

SMILES Cc1ccc(c(F)c1)C1(CC1)C(=O)Nc1ccc(-c2cnc(s2)C2CCC2)c(c1)C(O)=O

InChI Key InChIKey=UFCFKJIKEUMGFX-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 614789   

TargetB1 bradykinin receptor(Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM614789(US20230271931, Example 147 | 2-(2-Cyclobutyl- 1,3-...)
Affinity DataIC50: 13nMAssay Description:Notably, Compound Examples are tested in the FLIPR assays in the absence (hB1 free IC50) of 0.1% BSA in assay buffer, in order to assess the potency ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2023
Entry Details
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