BDBM614788 5-({[1-(4-Chloro- 2- fluorophenyl) cyclopropyl] carbonyl} amino)-2-(2- cyclobutyl-1,3- thiazol-5- yl)benzoic acid::US20230271931, Example 146

SMILES OC(=O)c1cc(NC(=O)C2(CC2)c2ccc(Cl)cc2F)ccc1-c1cnc(s1)C1CCC1

InChI Key InChIKey=XCZKFLRZKIEHIB-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 614788   

TargetB1 bradykinin receptor(Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM614788(US20230271931, Example 146 | 5-({[1-(4-Chloro- 2- ...)
Affinity DataIC50: 3.70nMAssay Description:Notably, Compound Examples are tested in the FLIPR assays in the absence (hB1 free IC50) of 0.1% BSA in assay buffer, in order to assess the potency ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2023
Entry Details
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