BDBM614781 2-(1-Ethyl-1H- pyrazol-4-yl)-3- fluoro-5-[({1-[2- fluoro-4- (trifluoromethoxy) phenyl]cyclo- propyl}carbonyl) amino]benzoic acid::US20230271931, Example 139

SMILES CCn1cc(cn1)-c1c(F)cc(NC(=O)C2(CC2)c2ccc(OC(F)(F)F)cc2F)cc1C(O)=O

InChI Key InChIKey=KIZISVSWHICRJX-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 614781   

TargetB1 bradykinin receptor(Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM614781(US20230271931, Example 139 | 2-(1-Ethyl-1H- pyrazo...)
Affinity DataIC50: 13nMAssay Description:Notably, Compound Examples are tested in the FLIPR assays in the absence (hB1 free IC50) of 0.1% BSA in assay buffer, in order to assess the potency ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2023
Entry Details
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