BDBM614742 3-Chloro-2-(1- cyclobutyl-1H- pyrazol-4-yl)-5- [({1-[2-fluoro-4- (trifluoromethyl) phenyl]cyclo- propyl}carbonyl) amino]benzoic acid::US20230271931, Example 100

SMILES OC(=O)c1cc(NC(=O)C2(CC2)c2ccc(cc2F)C(F)(F)F)cc(Cl)c1-c1cnn(c1)C1CCC1

InChI Key InChIKey=SRFKHESUWQNZBQ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 614742   

TargetB1 bradykinin receptor(Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM614742(US20230271931, Example 100 | 3-Chloro-2-(1- cyclob...)
Affinity DataIC50: 8.90nMAssay Description:Notably, Compound Examples are tested in the FLIPR assays in the absence (hB1 free IC50) of 0.1% BSA in assay buffer, in order to assess the potency ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2023
Entry Details
Go to US Patent

TargetB1 bradykinin receptor(Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM614742(US20230271931, Example 100 | 3-Chloro-2-(1- cyclob...)
Affinity DataIC50: 13nMAssay Description:Notably, Compound Examples are tested in the FLIPR assays in the presence (hB1 free IC50) of 0.1% BSA in assay buffer, in order to assess the potency...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2023
Entry Details
Go to US Patent