BDBM614739 2-[6-(1,1- Difluoropropyl) pyridin-3-yl]-3- fluoro-5-[({1-[2- fluoro-4- (trifluoromethoxy) phenyl]cyclo- propyl}carbonyl) amino]benzoic acid::US20230271931, Example 97

SMILES CCC(F)(F)c1ccc(cn1)-c1c(F)cc(NC(=O)C2(CC2)c2ccc(OC(F)(F)F)cc2F)cc1C(O)=O

InChI Key InChIKey=DEBRTGIYBVRSAV-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 614739   

TargetB1 bradykinin receptor(Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM614739(US20230271931, Example 97 | 2-[6-(1,1- Difluoropro...)
Affinity DataIC50: 10nMAssay Description:Notably, Compound Examples are tested in the FLIPR assays in the absence (hB1 free IC50) of 0.1% BSA in assay buffer, in order to assess the potency ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2023
Entry Details
Go to US Patent

TargetB1 bradykinin receptor(Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM614739(US20230271931, Example 97 | 2-[6-(1,1- Difluoropro...)
Affinity DataIC50: 25nMAssay Description:Notably, Compound Examples are tested in the FLIPR assays in the presence (hB1 free IC50) of 0.1% BSA in assay buffer, in order to assess the potency...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2023
Entry Details
Go to US Patent