BDBM614730 3-Fluoro-5-[({1- [2-fluoro-4- (trifluoromethyl) phenyl]cyclo- propyl}carbonyl) amino]-2-[1- (propan-2-yl)- 1H-pyrazol-4- yl]benzoic acid::US20230271931, Example 88

SMILES CC(C)n1cc(cn1)-c1c(F)cc(NC(=O)C2(CC2)c2ccc(cc2F)C(F)(F)F)cc1C(O)=O

InChI Key InChIKey=PXQWGKOLXPEPOR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 614730   

TargetB1 bradykinin receptor(Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM614730(US20230271931, Example 88 | 3-Fluoro-5-[({1- [2-fl...)
Affinity DataIC50: 32nMAssay Description:Notably, Compound Examples are tested in the FLIPR assays in the absence (hB1 free IC50) of 0.1% BSA in assay buffer, in order to assess the potency ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2023
Entry Details
Go to US Patent

TargetB1 bradykinin receptor(Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM614730(US20230271931, Example 88 | 3-Fluoro-5-[({1- [2-fl...)
Affinity DataIC50: 10nMAssay Description:Notably, Compound Examples are tested in the FLIPR assays in the presence (hB1 free IC50) of 0.1% BSA in assay buffer, in order to assess the potency...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2023
Entry Details
Go to US Patent