BDBM614719 2-[1-(2,2- Dimethylpropyl)- 1H-pyrazol-4- yl]-5-[({1-[2- fluoro-4- (trifluoromethoxy) phenyl]cyclo- propyl}carbonyl) amino]benzoic::US20230271931, Example 77

SMILES CC(C)(C)Cn1cc(cn1)-c1ccc(NC(=O)C2(CC2)c2ccc(OC(F)(F)F)cc2F)cc1C(O)=O

InChI Key InChIKey=JXTXIWVZORMYSW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 614719   

TargetB1 bradykinin receptor(Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM614719(US20230271931, Example 77 | 2-[1-(2,2- Dimethylpro...)
Affinity DataIC50: 17nMAssay Description:Notably, Compound Examples are tested in the FLIPR assays in the absence (hB1 free IC50) of 0.1% BSA in assay buffer, in order to assess the potency ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2023
Entry Details
Go to US Patent

TargetB1 bradykinin receptor(Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM614719(US20230271931, Example 77 | 2-[1-(2,2- Dimethylpro...)
Affinity DataIC50: 13nMAssay Description:Notably, Compound Examples are tested in the FLIPR assays in the presence (hB1 free IC50) of 0.1% BSA in assay buffer, in order to assess the potency...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2023
Entry Details
Go to US Patent