BDBM614682 2-(1-Cyclobutyl- 1H-pyrazol-4- yl)-5-({[1-(2,4- difluorophenyl) cyclopropyl] carbonyl}amino)- 3-fluorobenzoic acid::US20230271931, Example 40

SMILES OC(=O)c1cc(NC(=O)C2(CC2)c2ccc(F)cc2F)cc(F)c1-c1cnn(c1)C1CCC1

InChI Key InChIKey=OTKADLJLSKIEFF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 614682   

TargetB1 bradykinin receptor(Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM614682(US20230271931, Example 40 | 2-(1-Cyclobutyl- 1H-py...)
Affinity DataIC50: 16nMAssay Description:Notably, Compound Examples are tested in the FLIPR assays in the absence (hB1 free IC50) of 0.1% BSA in assay buffer, in order to assess the potency ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2023
Entry Details
Go to US Patent

TargetB1 bradykinin receptor(Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM614682(US20230271931, Example 40 | 2-(1-Cyclobutyl- 1H-py...)
Affinity DataIC50: 11nMAssay Description:Notably, Compound Examples are tested in the FLIPR assays in the presence (hB1 free IC50) of 0.1% BSA in assay buffer, in order to assess the potency...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2023
Entry Details
Go to US Patent