BDBM614667 2-(1-Cyclobutyl- 1H-pyrazol-4- yl)-3-fluoro-5- ({[1-(2-fluoro-4- methylphenyl) cyclopropyl] carbonyl}amino) benzoic acid::US20230271931, Example 25

SMILES Cc1ccc(c(F)c1)C1(CC1)C(=O)Nc1cc(F)c(-c2cnn(c2)C2CCC2)c(c1)C(O)=O

InChI Key InChIKey=SLZUUKYITSTWIN-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 614667   

TargetB1 bradykinin receptor(Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM614667(US20230271931, Example 25 | 2-(1-Cyclobutyl- 1H-py...)
Affinity DataIC50: 14nMAssay Description:Notably, Compound Examples are tested in the FLIPR assays in the absence (hB1 free IC50) of 0.1% BSA in assay buffer, in order to assess the potency ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2023
Entry Details
Go to US Patent

TargetB1 bradykinin receptor(Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM614667(US20230271931, Example 25 | 2-(1-Cyclobutyl- 1H-py...)
Affinity DataIC50: 5.90nMAssay Description:Notably, Compound Examples are tested in the FLIPR assays in the presence (hB1 free IC50) of 0.1% BSA in assay buffer, in order to assess the potency...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2023
Entry Details
Go to US Patent