BDBM61427 2-furanyl-[4-(2-methyl-5,6,7,8-tetrahydro-[1]benzothiolo[2,3-d]pyrimidin-4-yl)-1-piperazinyl]methanone::2-furyl-[4-(2-methyl-5,6,7,8-tetrahydrobenzothiopheno[2,3-d]pyrimidin-4-yl)piperazino]methanone::Furan-2-yl-[4-(2-methyl-5,6,7,8-tetrahydro-benzo[4,5]thieno[2,3-d]pyrimidin-4-yl)-piperazin-1-yl]-methanone::MLS000526305::SMR000116779::cid_1434953::furan-2-yl-[4-(2-methyl-5,6,7,8-tetrahydro-[1]benzothiolo[2,3-d]pyrimidin-4-yl)piperazin-1-yl]methanone

SMILES Cc1nc(N2CCN(CC2)C(=O)c2ccco2)c2c3CCCCc3sc2n1

InChI Key InChIKey=GDPDARVUXXOYAJ-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 61427   

TargetG-protein coupled receptor 55(Human)
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM61427(SMR000116779 | furan-2-yl-[4-(2-methyl-5,6,7,8-tet...)
Affinity DataIC50: 1.58E+3nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2011
Entry Details
PCBioAssay
TargetG-protein coupled receptor 55(Human)
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM61427(SMR000116779 | furan-2-yl-[4-(2-methyl-5,6,7,8-tet...)
Affinity DataIC50: 7.50E+3nMAssay Description:Antagonist activity at human GPR55 expressed in HEK293 cells coexpressing serum response element assessed as inhibition of LPI-induced MAPK/ERK signa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetG-protein coupled receptor 55(Human)
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM61427(SMR000116779 | furan-2-yl-[4-(2-methyl-5,6,7,8-tet...)
Affinity DataIC50: 700nMAssay Description:Antagonist activity at GPR55 (unknown origin) by beta-arrestin recruitment assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetG-protein coupled receptor 55(Human)
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM61427(SMR000116779 | furan-2-yl-[4-(2-methyl-5,6,7,8-tet...)
Affinity DataIC50: 2.02E+3nMAssay Description:Antagonist activity at beta-galactosidase fused human GPR55 expressed in CHO cells assessed as inhibition of LPI-induced receptor activation by measu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed