BDBM614210 US11746110, Example 5

SMILES CN1CCN(Cc2ccc(cc2C(F)(F)F)C(=O)Nc2ccc(C)c(c2)C#Cc2cnc3c(Nc4cnn(C)c4)nccn23)CC1

InChI Key InChIKey=QTVCDMUYWFDBGF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 614210   

TargetTyrosine-protein kinase ABL1(Human)
Shenzhen Targetrx

US Patent
LigandPNGBDBM614210(US11746110, Example 5)
Affinity DataIC50: 3.33nMAssay Description:Reagents and materials: ABL (ThermoFisher, Cat. No. PV3585), ABL T315I(Thermo Fisher, Cat. No. PR7429B), Ret (Carna, Cat. No. 08-159-10 ug), RET...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2023
Entry Details
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TargetTyrosine-protein kinase ABL1 [T315I](Human)
Shenzhen Targetrx

US Patent
LigandPNGBDBM614210(US11746110, Example 5)
Affinity DataIC50: 3.44nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2023
Entry Details
Go to US Patent