BDBM614088 US11744824, Example 101

SMILES Nc1nc2ccc(cn2c1C(=O)[C@@H]1C[C@@H]1F)-c1c(F)ccc2[nH]ccc12

InChI Key InChIKey=XYAAWEWZLXWLEM-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 614088   

TargetReceptor-interacting serine/threonine-protein kinase 2(Human)
1St Biotherapeutics

US Patent
LigandPNGBDBM614088(US11744824, Example 101)
Affinity DataIC50: 100nMAssay Description:GST-tagged recombinant human RIP2 (25 ng) is incubated with 5 μL of compounds (0.5% DMSO), 5 μL of MBP (0.5 μg/μl) and 5 μL ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2023
Entry Details
Go to US Patent