BDBM613676 3-[({(1S)-6-[4-(cyclopropyl- 1,2,3,4-tetrahydroisoquinolyl} methyl)amino]pyridine-4- carboxylic acid; and 3-[({(1R)- 6-[4-(cyclopropyl- methoxy)-2-methylphenyl]- 1,2,3,4-tetrahydro- isoquinolyl}methyl) amino]pyridine-4-carboxylic acid::US11731954, Example 4A and 4B

SMILES Cc1cc(OCC2CC2)ccc1-c1ccc2C(CNc3cnccc3C(O)=O)NCCc2c1

InChI Key InChIKey=VVERAQBWHULSTJ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 613676   

TargetLysine-specific demethylase 4C(Human)
Celgene Quanticel Research

US Patent
LigandPNGBDBM613676(US11731954, Example 4A and 4B | 3-[({(1S)-6-[4-(cy...)
Affinity DataIC50: 550nMAssay Description:The ability of test compounds to inhibit the activity of JMJD2C was determined in 384-well plate format under the following reaction conditions: 0.3 ...More data for this Ligand-Target Pair
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Date in BDB:
9/26/2023
Entry Details
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TargetLysine-specific demethylase 6B(Human)
Celgene Quanticel Research

US Patent
LigandPNGBDBM613676(US11731954, Example 4A and 4B | 3-[({(1S)-6-[4-(cy...)
Affinity DataIC50: 1.00E+4nMAssay Description:The enzymatic assay of JMJD3 activity is based upon Time Resolved-Fluorescence Resonance Energy Transfer (TR-FRET) detection. The ability of test com...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2023
Entry Details
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TargetLysine-specific demethylase 5B(Human)
Celgene Quanticel Research

US Patent
LigandPNGBDBM613676(US11731954, Example 4A and 4B | 3-[({(1S)-6-[4-(cy...)
Affinity DataIC50: 100nMAssay Description:The ability of test compounds to inhibit the activity of Jarid1B was determined in 384-well plate format under the following reaction conditions: 0.8...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2023
Entry Details
Go to US Patent