BDBM613251 N-[(2-{[(1-{3- fluorobicyclo [1.1.1]pentan-1- yl}ethyl)amino] methyl}-1H- indol-6- yl)methyl]-4- oxo-4H- pyrido[1,2- a]pyrimidine-2- carboxamide::US11725010, Example 120

SMILES CC(NCc1cc2ccc(CNC(=O)c3cc(=O)n4ccccc4n3)cc2[nH]1)C12CC(F)(C1)C2

InChI Key InChIKey=YUORQJPNKZSTOG-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 613251   

LigandPNGBDBM613251(US11725010, Example 120 | N-[(2-{[(1-{3- fluorobic...)
Affinity DataIC50: 6.10nMAssay Description:The enzymatic assay was established to determine IC50 values for inhibition of RNA methyltransferase activity. The enzyme used was full-length his-ta...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2023
Entry Details
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TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM613251(US11725010, Example 120 | N-[(2-{[(1-{3- fluorobic...)
Affinity DataIC50: 6.10nMAssay Description:Inhibition of full-length His-tagged METTL3/full length FLAG-tagged METTL14 (unknown origin) expressed in baculovirus expression system using synthet...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed