BDBM612379 2-(4-chloro-benzyl)-7-mehtyl-5-(3-piperazin-1-ylmethyl- [1,2,4]oxadiazol-5-yl)-2,3-dihydro-isoindol-1-one::US20240050427, Compound 4

SMILES Cc1cc(cc2CN(Cc3ccc(Cl)cc3)C(=O)c12)-c1nc(CN2CCNCC2)no1

InChI Key InChIKey=QKSTZJGOYWJNSO-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 612379   

TargetMetabotropic glutamate receptor 2(Human)
Sirgartan Holdings

US Patent
LigandPNGBDBM612379(2-(4-chloro-benzyl)-7-mehtyl-5-(3-piperazin-1-ylme...)
Affinity DataEC50:  378nMAssay Description:The compounds described herein have been shown to be positive allosteric modulators of the mGluR2 receptor using a [35S]-GTPγS binding assay as ...More data for this Ligand-Target Pair
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Date in BDB:
4/23/2024
Entry Details
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