BDBM612377 BDBM612516::BDBM612517::N'-(1,2,3,5,6,7-hexahydro-s- indacen-4-ylcarbamoyl)-4-(2- hydroxypropan-2-yl)thiophene-2- sulfonimidamide::US11724992, Example 74

SMILES CC(C)(O)c1csc(c1)S(N)(=O)=NC(=O)Nc1c2CCCc2cc2CCCc12

InChI Key InChIKey=JCQRNNNBOOKAPS-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 612377   

LigandPNGBDBM612377(N'-(1,2,3,5,6,7-hexahydro-s- indacen-4-ylcarbamoyl...)
Affinity DataIC50: 24nMAssay Description:THP-1 cells were purchased from the American Type Culture Collection and sub-cultured according to instructions from the supplier. Prior to experimen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2023
Entry Details
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LigandPNGBDBM612377(N'-(1,2,3,5,6,7-hexahydro-s- indacen-4-ylcarbamoyl...)
Affinity DataIC50: 600nMAssay Description:THP-1 cells were purchased from the American Type Culture Collection and sub-cultured according to instructions from the supplier. Prior to experimen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2023
Entry Details
Go to US Patent

LigandPNGBDBM612377(N'-(1,2,3,5,6,7-hexahydro-s- indacen-4-ylcarbamoyl...)
Affinity DataIC50: 24nMAssay Description:THP-1 cells were purchased from the American Type Culture Collection and sub-cultured according to instructions from the supplier. Prior to experimen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2023
Entry Details
Go to US Patent