BDBM612360 2-(4-chlorobenzyl)-7-methyl-5-[3-(3-methyl-piperazin-1- ylmethyl)-[1,2,4]oxadiazol-5-yl]-2,3-dihydro-isoindol-1-one::US20240050427, Compound 3

SMILES CC1CN(Cc2noc(n2)-c2cc3CN(Cc4ccc(Cl)cc4)C(=O)c3c(C)c2)CCN1

InChI Key InChIKey=RXCGBWASQPHYQR-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 612360   

TargetMetabotropic glutamate receptor 2(Human)
Sirgartan Holdings

US Patent
LigandPNGBDBM612360(2-(4-chlorobenzyl)-7-methyl-5-[3-(3-methyl-piperaz...)
Affinity DataEC50:  154nMAssay Description:The compounds described herein have been shown to be positive allosteric modulators of the mGluR2 receptor using a [35S]-GTPγS binding assay as ...More data for this Ligand-Target Pair
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Date in BDB:
4/23/2024
Entry Details
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