BDBM612358 BDBM612488::BDBM612489::N'-((8-fluoro-1,2,3,5,6,7- hexahydro-s-indacen-4- yl)carbamoyl)-2-(2- hydroxypropan-2-yl)-4- methylthiazole-5- sulfonimidamide::US11724992, Example 59

SMILES Cc1nc(sc1S(N)(=O)=NC(=O)Nc1c2CCCc2c(F)c2CCCc12)C(C)(C)O

InChI Key InChIKey=DIPAYQSANQORKG-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 612358   

LigandPNGBDBM612358(US11724992, Example 59 | BDBM612489 | BDBM612488 |...)
Affinity DataIC50: 24nMAssay Description:THP-1 cells were purchased from the American Type Culture Collection and sub-cultured according to instructions from the supplier. Prior to experimen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2023
Entry Details
Go to US Patent

LigandPNGBDBM612358(US11724992, Example 59 | BDBM612489 | BDBM612488 |...)
Affinity DataIC50: 24nMAssay Description:THP-1 cells were purchased from the American Type Culture Collection and sub-cultured according to instructions from the supplier. Prior to experimen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2023
Entry Details
Go to US Patent

LigandPNGBDBM612358(US11724992, Example 59 | BDBM612489 | BDBM612488 |...)
Affinity DataIC50: 3.00E+3nMAssay Description:THP-1 cells were purchased from the American Type Culture Collection and sub-cultured according to instructions from the supplier. Prior to experimen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2023
Entry Details
Go to US Patent