BDBM612295 1-(5-(4-((4-([1,2,4]triazolo[1,5- c]pyrimidin-7-yloxy)-3- methylphenyl)amino)-5-(3- (dimethylamino)azetidin-1- yl)quinazolin-7-yl)-3,6- dihydropyridin-1(2H)-yl)prop-2- en-1-one::US11723908, Example 84

SMILES CN(C)C1CN(C1)c1cc(cc2ncnc(Nc3ccc(Oc4cc5ncnn5cn4)c(C)c3)c12)C1=CCCN(C1)C(=O)C=C

InChI Key InChIKey=CKOFGCXDBATTOY-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 612295   

TargetReceptor tyrosine-protein kinase erbB-2(Human)
Suzhou Zanrong Pharma

US Patent
LigandPNGBDBM612295(US11723908, Example 84 | 1-(5-(4-((4-([1,2,4]triaz...)
Affinity DataIC50: 207nMAssay Description:Inhibition of phosphor HER2 was determined by enzyme-linked immunosorbent assay (ELISA) in BT474 cells. BT474 cell line was purchased from ATCC (cata...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2023
Entry Details
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