BDBM612290 2-(4-chloro-benzyl)-5-[3-(2,5-diaza-bicyclo[2.2.1]hept-2- ylmethyl)-[1,2,4]oxadiazol-5-yl]-7-methyl-2,3-dihydro- isoindol-1-one::US20240050427, Compound 2

SMILES Cc1cc(cc2CN(Cc3ccc(Cl)cc3)C(=O)c12)-c1nc(CN2C[C@H]3C[C@@H]2CN3)no1

InChI Key InChIKey=BTXFSYKEPWTYTB-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 612290   

TargetMetabotropic glutamate receptor 2(Human)
Sirgartan Holdings

US Patent
LigandPNGBDBM612290(2-(4-chloro-benzyl)-5-[3-(2,5-diaza-bicyclo[2.2.1]...)
Affinity DataEC50:  206nMAssay Description:The compounds described herein have been shown to be positive allosteric modulators of the mGluR2 receptor using a [35S]-GTPγS binding assay as ...More data for this Ligand-Target Pair
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Date in BDB:
4/23/2024
Entry Details
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