BDBM612282 (R)-N-(4-([1,2,4]-triazolo[1,5-c]pyrimidin-7-yloxy)-3-methylphenyl)-5-((3,3-difluoro-1-methylpiperidin-4-yl)oxy)-6-(trifluoromethoxy)quinazolin-4-amine::US11723908, Example 72

SMILES CN1CC[C@@H](Oc2c(OC(F)(F)F)ccc3ncnc(Nc4ccc(Oc5cc6ncnn6cn5)c(C)c4)c23)C(F)(F)C1

InChI Key InChIKey=JYPFZIHUICGFBF-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 612282   

TargetReceptor tyrosine-protein kinase erbB-2(Human)
Suzhou Zanrong Pharma

US Patent
LigandPNGBDBM612282(US11723908, Example 72 | (R)-N-(4-([1,2,4]-triazol...)
Affinity DataIC50: 51nMAssay Description:Inhibition of phosphor HER2 was determined by enzyme-linked immunosorbent assay (ELISA) in BT474 cells. BT474 cell line was purchased from ATCC (cata...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2023
Entry Details
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