BDBM611895 (2R,3R,11bR)-3-(2,2- dimethylpropyl)-10-methoxy- 9-[(2S)-3,3,3-trifluoro-2- hydroxypropoxy]- 1H,2H,3H,4H,6H,7H,11bH- pyrido[2,1-a]isoquinolin-2-ol::US11718618, Compound 4-50

SMILES COc1cc2[C@H]3C[C@@H](O)[C@H](CC(C)(C)C)CN3CCc2cc1OC[C@H](O)C(F)(F)F

InChI Key InChIKey=ROUGUCFWHYJEOY-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 611895   

TargetSynaptic vesicular amine transporter(Human)
Neurocrine Biosciences

US Patent
LigandPNGBDBM611895(US11718618, Compound 4-50 | (2R,3R,11bR)-3-(2,2- d...)
Affinity DataKi:  1.40nMAssay Description:The human VMAT2 Ki values for the compounds listed in Table 15A and Table 15B were determined using the following procedures. Compound dilution serie...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/17/2023
Entry Details
Go to US Patent