BDBM611801 US11718612, Example 90

SMILES Cc1ccc(Cn2cnc(n2)C(=O)Nc2cccc(Cl)c2F)cn1

InChI Key InChIKey=ISWZZRCPHLDRNT-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 611801   

TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
University Of Texas

US Patent
LigandPNGBDBM611801(US11718612, Example 90)
Affinity DataIC50: 1.46E+3nMAssay Description:In order to measure RIPK1 activity the ADP-Glo kinase assay (Promega, Catalog #V7002) was used to measure the conversion of ATP to ADP. This enzymati...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/15/2023
Entry Details
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