BDBM611777 2-benzyl-3-chloro-7-(3- chlorophenyl)-6,7- dihydroimidazo[1,2- a]pyrazin-8(5H)-one::US11718612, Example 42

SMILES Clc1c(Cc2ccccc2)nc2C(=O)N(CCn12)c1cccc(Cl)c1

InChI Key InChIKey=WTWXXOFLPNGHMN-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 611777   

TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
University Of Texas

US Patent

LigandBDBM611777(US11718612, Example 42 | 2-benzyl-3-chloro-7-(3- c...)Copy SMILESCopy InChI

Affinity DataIC50: 318nMAssay Description:In order to measure RIPK1 activity the ADP-Glo kinase assay (Promega, Catalog #V7002) was used to measure the conversion of ATP to ADP. This enzymati...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProtUniProtKB/TrEMBL
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
9/15/2023
Entry Details
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