BDBM611773 1-benzyl-N-(3-chloro-2- fluoro-5-(trifluoro- methyl)phenyl)-1H- 1,2,4-triazole-3- carboxamide::US11718612, Example 38

SMILES Fc1c(Cl)cc(cc1NC(=O)c1ncn(Cc2ccccc2)n1)C(F)(F)F

InChI Key InChIKey=QVENILDGFMTAHN-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 611773   

TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
University Of Texas

US Patent

LigandBDBM611773(US11718612, Example 38 | 1-benzyl-N-(3-chloro-2- f...)Copy SMILESCopy InChI

Affinity DataIC50: 1.30E+3nMAssay Description:In order to measure RIPK1 activity the ADP-Glo kinase assay (Promega, Catalog #V7002) was used to measure the conversion of ATP to ADP. This enzymati...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProtUniProtKB/TrEMBL
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
9/15/2023
Entry Details
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