BDBM611768 N-(3-chloro-2-fluoro- phenyl)-1-(4-cyano- benzyl)-1H-1,2,4- triazole-3-carboxamide::US11718612, Example 33

SMILES Fc1c(Cl)cccc1NC(=O)c1ncn(Cc2ccc(cc2)C#N)n1

InChI Key InChIKey=LFOZSZIHVAFDNX-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 611768   

TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
University Of Texas

US Patent
LigandPNGBDBM611768(US11718612, Example 33 | N-(3-chloro-2-fluoro- phe...)
Affinity DataIC50: 389nMAssay Description:In order to measure RIPK1 activity the ADP-Glo kinase assay (Promega, Catalog #V7002) was used to measure the conversion of ATP to ADP. This enzymati...More data for this Ligand-Target Pair
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Date in BDB:
9/15/2023
Entry Details
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